Product Details – Orexin B
Orexin B is a neuropeptide derived from the precursor molecule prepro-orexin, which is processed into orexin A and orexin B through enzymatic cleavage. It is naturally associated with hypothalamic signaling systems and is studied for its role in neuropeptide-receptor interactions.
In controlled laboratory environments, orexin B is utilized to investigate receptor binding behavior and intracellular signaling pathways associated with neuropeptide activity. Its defined amino acid structure allows for consistent evaluation of peptide-receptor dynamics and signal transduction mechanisms.
This compound is supplied strictly for laboratory research purposes and is not intended for consumption, medical, or diagnostic use.
Mechanism of Action
At the molecular level, orexin B is studied for its interaction with orexin receptors, particularly orexin receptor 2 (OX2R), which belongs to the G protein-coupled receptor (GPCR) family. Upon binding, the receptor-ligand complex initiates intracellular signaling cascades, including calcium ion mobilization and downstream second messenger activity.
These signaling events are analyzed in vitro to evaluate receptor activation, ligand affinity, and intracellular communication pathways. Researchers examine how orexin B influences neurotransmitter-related signaling systems through receptor-mediated mechanisms.
Additionally, orexin B is investigated for its role in modulating neuropeptide signaling networks, contributing to a broader understanding of receptor-specific activation and molecular pathway regulation under controlled experimental conditions.
Chemical Properties of Orexin B
| Attribute | Details |
| Compound Name | Orexin B |
| Classification | Neuropeptide (hypocretin-2) |
| Molecular Formula | C123H212N44O35S |
| Molecular Weight | 2899.3 g/mol |
| CAS Number | 205640-91-1 |
| PubChem CID | 44404987 |
| Synonyms | Hypocretin-2; Orexin-B |
| Primary Target | Orexin receptor 2 (OX2R) |
| Research Context | Neuropeptide signaling and receptor interaction studies |
| Format | Research peptide (non-consumable) |
| Stability | Maintained under controlled laboratory storage conditions |
Research Applications
Receptor Binding Studies
Orexin B is utilized in experimental systems to evaluate ligand interaction with orexin receptors. Researchers analyze binding affinity, receptor activation, and signal initiation at the molecular level.
Intracellular Signaling Analysis
This compound is applied in studies examining GPCR-mediated signaling pathways, including calcium-dependent signaling and second messenger systems. These investigations focus on intracellular communication and pathway regulation.
Neuropeptide Interaction Research
Orexin B supports investigations into peptide-mediated signaling networks, including interactions with neurotransmitter-associated pathways. These studies contribute to a broader understanding of neuropeptide function at the molecular level.
Why Choose PEPTIDES GLOBAL LAB to Buy Orexin B for Research
Peptides Global Lab supplies research-grade Orexin B produced under controlled laboratory conditions with strict quality assurance protocols in place. Each batch undergoes detailed analytical verification to ensure consistency in molecular composition and purity.
In addition, comprehensive documentation, including laboratory testing reports and sourcing transparency, supports reproducibility across experimental applications. Peptides Global Lab maintains a compliance-focused approach, ensuring that all compounds are supplied exclusively for laboratory-based investigation and analytical research.
Disclaimer
Orexin B is intended strictly for laboratory research and analytical purposes only. It is not designed for diagnostic procedures, therapeutic applications, or any form of in vivo study.
All references to biochemical pathways, receptor interactions, and enzymatic processes are provided solely within a research context. This compound must be handled only by qualified professionals within controlled laboratory environments, in accordance with applicable regulations and safety standards.
Any use outside of these defined research conditions is strictly prohibited.




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